Before-And-After Pics Make Rebel Wilson's Face Transformation From Weight Loss Apparent

Rebel Wilson's complete weight-loss transformation had quite the effect on her face. The changes that the "Pitch Perfect" star's face underwent as she lost over 80 lbs. are obvious in side-by-side photos taken in 2019 and 2025. The overall loss of volume has brought a minor loss of skin elasticity, which is particularly visible in her cheeks, neck, and the area around her lips and eyes. In the 2025 photo, Wilson also has a sharper jawline, and her neck muscles are more visible. After looking at photos of Wilson's transformation, people deemed her one of the many celebrities who looked completely different after taking weight loss drugs like Ozempic. 

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For her part, the Australian actor has maintained that the diabetes drug didn't play a huge role in her weight-loss transformation. Speaking to USA Today in September 2025, Wilson shared that her OB/GYN had recommended that she start taking Ozempic after she lost weight because the medical professional feared that she would have a hard time maintaining her progress. After "microdosing" GLP-1 medication for several months, Wilson committed to a 10-week program right before she married Ramona Agruma in September 2024. 

Wilson explained that she made the decision because she believed that losing a few pounds would make her look even better in her wedding dress. At the time of the interview, the "Jojo Rabbit" star was using GLP-1 medication in microdoses so she could maintain her weight loss as she navigated a stressful work schedule and cared for her young daughter.

Speaking to The Times in March 2024, Rebel Wilson shared that she had dubbed 2020 her "year of health" after a fertility doctor informed her that she would have a greater shot at getting pregnant through IVF if she lost weight. While the comedian felt determined to make the change, most of her inner circle was iffy about the idea because they feared that she would lose her niche in the industry as the "fat funny character" if she lost weight. 

Wilson rightfully didn't let the doubters get to her and started doing what she felt was right for her body. To start, the "Bridesmaids" star promised herself that she wouldn't do anything over-the-top to achieve her weight-loss goals. Instead, she turned her focus towards limiting her sugar intake, consuming protein-rich meals, and getting in more steps daily. When Wilson appeared on "The Drew Barrymore Show" in November 2020, she shared that she had tried her fair share of fad diets over the years. Since they were to no avail, Wilson decided to take a different road and focus on the psychological aspects of her diet. 

On her health journey, the "Senior Year" star realized that she was constantly consuming excessive amounts of sugar to deal with the emotional toll of being successful. Wilson ultimately had to get to the root cause of her emotional eating and her diminished self-worth to be able to achieve her weight-loss goals. If all of that wasn't impressive enough already, Rebel Wilson also managed to have a stunning style transformation in her "year of health."